Less Common Liver Conditions

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Some less common disorders of the liver include:

Alpha-1 antitrypsin deficiency

This is a condition that is passed on from parents to their children through genes. This condition may result in serious lung and/or liver disease at various ages in life.
Learn more about Alpha-1.   Alpha-1 Liver disease.   See a fact sheet.

Autoimmune liver disorders

These disorders see an abnormal increase in immune cells that damage the liver cells. Autoimmune Hepatitis is a serious condition that may worsen over time if not treated, which can lead to cirrhosis and liver failure.

These rare conditions include autoimmune hepatitis and primary biliary cirrhosis (mostly affecting women) and primary sclerosing cholangitis (more common in men). Learn more.


This is a rare inherited disorder  where the body’s reaction to particular milk sugars damages the liver and other organs. Learn more.


This inherited disease makes the body absorb and store higher than normal amounts of iron damaging many organs including the liver, pancreas and heart. Learn more.

Wilson’s disease

Wilson’s disease occurs when the liver can’t excrete copper. Various organs of the body, including the liver and brain, are affected by the excessively high copper levels.  Learn more.

Stigma & Discrimination

People who live with a liver condition such as hepatitis B or hepatitis C, have reported been discriminated against.

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LiverWELL observes and honours the Kulin Nation's intrinsic connection to land, sky and water, and the creator Bunjil. LiverWELL is committed to being led and informed by Aboriginal and Torres Strait Islanders on bridging health outcomes for communities and improving liver health.